Research Articles Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice. admin April 9, 2020 Infect Immun. 2013 Mar;81(3):789-800. doi: 10.1128/IAI.01108-12. https://www.ncbi.nlm.nih.gov/pubmed/23275094 Read More Share
Research Articles Association of antibodies to Plasmodium falciparum reticulocyte binding protein homolog 5 with protection from clinical malaria. admin April 9, 2020 Front Microbiol. 2014 Jun 30;5:314. doi: 10.3389/fmicb.2014.00314. eCollection 2014. PubMed PMID: 25071730; PubMed Central PMCID: PMC4074990. https://www.ncbi.nlm.nih.gov/pubmed/?term=25071730 Read More Share
Research Articles Transmission-blocking activity of antibodies to Plasmodium falciparum GLURP.10C chimeric protein formulated in different adjuvants. admin April 9, 2020 Malar J. 2015 Nov 9;14:443. doi: 10.1186/s12936-015-0972-0. PubMed PMID: 26552428; PubMed Central PMCID: PMC4640242. https://www.ncbi.nlm.nih.gov/pubmed/?term=26552428 Read More Share
Research Articles Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection. admin April 9, 2020 NPJ Vaccines. 2017;2. pii: 10. doi: 10.1038/s41541-017-0011-y. Epub 2017 Apr 10. PubMed PMID: 28936360; PubMed Central PMCID: PMC5603302. https://www.ncbi.nlm.nih.gov/pubmed/?term=28936360 Read More Share
Research Articles HRI, a stress response eIF2α kinase, exhibits structural and functional stability at high temperature and alkaline conditions. admin April 9, 2020 Int J Biol Macromol. 2017 Feb;95:528-538. doi: 10.1016/j.ijbiomac.2016.11.071. Epub 2016 Nov 22. PubMed PMID: 27888007. https://www.ncbi.nlm.nih.gov/pubmed/?term=27888007 Read More Share
Research Articles Elucidation of molecular mechanism of stability of the heme-regulated eIF2α kinase upon binding of its ligand, hemin in its catalytic kinase domain. admin April 9, 2020 J Biomol Struct Dyn. 2018 Aug;36(11):2845-2861. doi: 10.1080/07391102.2017.1368417. Epub 2017 Sep 12. PubMed PMID: 28814160. https://www.ncbi.nlm.nih.gov/pubmed/?term=28814160 Read More Share
Research Articles Activation of HRI is mediated by Hsp90 during stress through modulation of the HRI-Hsp90 complex. admin April 9, 2020 Int J Biol Macromol. 2018 Oct 15;118(Pt B):1604-1613. doi: 10.1016/j.ijbiomac.2018.06.204. Epub 2018 Jul 3. PubMed PMID: 30170366. https://www.ncbi.nlm.nih.gov/pubmed/?term=30170366 Read More Share
Research Articles The Leishmania donovani IMPACT-like protein possesses non-specific nuclease activity. admin April 9, 2020 Int J Biol Macromol. 2018 Nov;119:962-973. doi: 10.1016/j.ijbiomac.2018.07.175 https://www.ncbi.nlm.nih.gov/pubmed/30077668 Read More Share
Research Articles Malaria vaccine candidate based on Duffy-binding protein elicits strain transcending functional antibodies in a Phase I trial. admin April 9, 2020 NPJ Vaccines. 2018 Sep 28;3:48. doi: 10.1038/s41541-018-0083-3. eCollection 2018. PubMed PMID: 30302285; PubMed Central PMCID: PMC6162314. https://www.ncbi.nlm.nih.gov/pubmed/?term=30302285 Read More Share
Research Articles The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable. admin April 9, 2020 J Biol Chem. 2020 Jan 10;295(2):403-414. doi: 10.1074/jbc.RA119.011268. https://www.ncbi.nlm.nih.gov/pubmed/31792057 Read More Share